Developing TPACK is a focus of the Teaching Teachers for the Future project. This recent paper provides some ideas about design of courses using a 'learning technology by design' approach to develop TPACK.
Koehler, M. J., Mishra, P., Bouck, E. C., DeSchryver, M., Kereluik, K., Shin, T. S., et al. (2011). Deep-play: developing TPACK for 21st century teachers. International Journal of Learning Technology, 6(2), 146-163. The references to play and creativity link well with other material I've been reading recently about creativity and the education as preparation for living with surprises.